Variation Browser
DownloadReceptor | Position | GPCRdb | Segment | Variant | Mutation type | Allele Frequency | Allele Count | Allele Number | Homozygotes | SIFT score | PolyPhen score | Functional annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Receptor | Position | GPCRdb | Segment | Variant | Mutation Type | Allele Frequency | Allele Count | Allele Number | Homozygotes | SIFT score | PolyPhen score | Functional annotation |
ssr5_human | 4 | N-term | L => ValfsTer21 | frameshift | 3.122e-05 | 3 | 96088 | 0 | None | None | ||
ssr5_human | 42 | 1.34x34 | TM1 | L => TrpfsTer30 | frameshift | 1.648e-05 | 1 | 60682 | 0 | None | None | |
ssr5_human | 123 | 3.36x36 | TM3 | Q => Ter | stop gained | 8.41e-06 | 1 | 118906 | 0 | None | None | |
ssr5_human | 166 | 4.52x52 | TM4 | L => ArgfsTer61 | frameshift | 1.068e-05 | 1 | 93592 | 0 | None | None | |
ssr5_human | 197 | 5.34x35 | TM5 | W => Ter | stop gained | 9.891e-06 | 1 | 101106 | 0 | None | None | |
ssr5_human | 237 | 6.24x24 | TM6 | C => TrpfsTer12 | frameshift | 8.622e-06 | 1 | 115986 | 0 | None | None | |
ssr5_human | 308 | 8.47x47 | H8 | S => ThrfsTer82 | frameshift | 4.186e-05 | 5 | 119456 | 0 | None | None | GP (contact) |
ssr5_human | 7 | N-term | A => D | missense | 2.146e-05 | 2 | 93176 | 0 | 0.39 | 0.371 | ||
ssr5_human | 8 | N-term | S => T | missense | 1.077e-05 | 1 | 92812 | 0 | 0.4 | 0.011 | ||
ssr5_human | 9 | N-term | T => M | missense | 0.001259 | 115 | 91372 | 0 | 0.33 | 0.056 | ||
ssr5_human | 9 | N-term | T => R | missense | 1.094e-05 | 1 | 91372 | 0 | 0.5 | 0.019 | ||
ssr5_human | 14 | N-term | A => T | missense | 0.0006265 | 53 | 84602 | 0 | 0.66 | 0.006 | ||
ssr5_human | 17 | N-term | P => L | missense | 8.831e-05 | 7 | 79266 | 0 | 0.31 | 0.004 | ||
ssr5_human | 17 | N-term | P => R | missense | 3.785e-05 | 3 | 79266 | 0 | 0.34 | 0.242 | ||
ssr5_human | 18 | N-term | G => R | missense | 0.0001389 | 11 | 79166 | 0 | 0.14 | 0.005 | ||
ssr5_human | 24 | N-term | G => S | missense | 8.394e-05 | 6 | 71482 | 0 | 0.99 | 0.003 | ||
ssr5_human | 26 | N-term | N => Y | missense | 1.416e-05 | 1 | 70638 | 0 | 0.03 | 0.957 | ||
ssr5_human | 28 | N-term | T => M | missense | 5.826e-05 | 4 | 68656 | 0 | 0.0 | 0.927 | ||
ssr5_human | 32 | N-term | P => L | missense | 9.65e-05 | 6 | 62174 | 0 | 0.35 | 0.003 | ||
ssr5_human | 33 | N-term | A => V | missense | 7.981e-05 | 5 | 62646 | 0 | 0.57 | 0.006 | ||
ssr5_human | 35 | N-term | S => L | missense | 1.631e-05 | 1 | 61318 | 0 | 0.33 | 0.006 | ||
ssr5_human | 37 | 1.29x29 | TM1 | G => R | missense | 3.373e-05 | 2 | 59296 | 0 | 0.2 | 0.892 | |
ssr5_human | 39 | 1.31x31 | TM1 | R => Q | missense | 0.000207 | 12 | 57968 | 0 | 0.31 | 0.016 | |
ssr5_human | 40 | 1.32x32 | TM1 | A => V | missense | 6.793e-05 | 4 | 58884 | 0 | 0.1 | 0.014 | |
ssr5_human | 45 | 1.37x37 | TM1 | V => L | missense | 1.568e-05 | 1 | 63794 | 0 | 1.0 | 0.025 | |
ssr5_human | 45 | 1.37x37 | TM1 | V => M | missense | 1.568e-05 | 1 | 63794 | 0 | 0.04 | 0.632 | |
ssr5_human | 46 | 1.38x38 | TM1 | L => P | missense | 1.514e-05 | 1 | 66054 | 0 | 0.0 | 0.966 | |
ssr5_human | 48 | 1.40x40 | TM1 | L => M | missense | 0.05283 | 3677 | 69606 | 92 | 0.08 | 0.998 | |
ssr5_human | 52 | 1.44x44 | TM1 | A => V | missense | 0.08092 | 6301 | 77866 | 332 | 1.0 | 0.014 | |
ssr5_human | 54 | 1.46x46 | TM1 | G => R | missense | 1.18e-05 | 1 | 84780 | 0 | 0.0 | 1.0 | |
ssr5_human | 58 | 1.50x50 | TM1 | N => T | missense | 1.031e-05 | 1 | 96948 | 0 | 0.02 | 0.999 | |
ssr5_human | 62 | 1.54x54 | TM1 | I => L | missense | 1.889e-05 | 2 | 105884 | 0 | 0.0 | 0.527 | |
ssr5_human | 63 | 1.55x55 | TM1 | Y => H | missense | 9.333e-06 | 1 | 107152 | 0 | 0.16 | 0.975 | |
ssr5_human | 67 | 1.59x59 | TM1 | R => C | missense | 0.0001068 | 12 | 112340 | 0 | 0.02 | 0.135 | PTM (Methylation) |
ssr5_human | 69 | 12.48x48 | ICL1 | A => T | missense | 8.718e-06 | 1 | 114708 | 0 | 0.33 | 0.174 | |
ssr5_human | 74 | 2.38x38 | TM2 | V => I | missense | 2.553e-05 | 3 | 117492 | 0 | 0.09 | 0.753 | |
ssr5_human | 85 | 2.49x49 | TM2 | A => V | missense | 8.413e-06 | 1 | 118868 | 0 | 0.0 | 0.999 | |
ssr5_human | 86 | 2.50x50 | TM2 | D => N | missense | 5.045e-05 | 6 | 118930 | 0 | 0.0 | 1.0 | |
ssr5_human | 87 | 2.51x51 | TM2 | V => I | missense | 2.521e-05 | 3 | 118978 | 0 | 0.03 | 0.135 | |
ssr5_human | 90 | 2.54x54 | TM2 | M => V | missense | 8.398e-06 | 1 | 119082 | 0 | 0.02 | 0.345 | |
ssr5_human | 93 | 2.57x57 | TM2 | L => M | missense | 8.396e-06 | 1 | 119104 | 0 | 0.0 | 1.0 | |
ssr5_human | 93 | 2.57x57 | TM2 | L => R | missense | 1.679e-05 | 2 | 119124 | 0 | 0.0 | 1.0 | |
ssr5_human | 98 | 2.62x62 | TM2 | T => M | missense | 8.39e-06 | 1 | 119194 | 0 | 0.1 | 0.994 | |
ssr5_human | 101 | 2.65x65 | TM2 | A => T | missense | 8.388e-05 | 10 | 119220 | 0 | 0.06 | 0.283 | |
ssr5_human | 102 | 2.66x66 | TM2 | A => T | missense | 0.000109 | 13 | 119236 | 0 | 0.0 | 0.196 | |
ssr5_human | 107 | 23.52x52 | ECL1 | F => C | missense | 8.39e-06 | 1 | 119196 | 0 | 0.0 | 0.999 | |
ssr5_human | 108 | 3.21x21 | TM3 | G => S | missense | 2.517e-05 | 3 | 119188 | 0 | 0.0 | 1.0 | |
ssr5_human | 109 | 3.22x22 | TM3 | P => S | missense | 0.05714 | 6809 | 119162 | 325 | 1.0 | 0.026 | |
ssr5_human | 109 | 3.22x22 | TM3 | P => T | missense | 8.392e-06 | 1 | 119162 | 0 | 0.1 | 0.257 | |
ssr5_human | 110 | 3.23x23 | TM3 | V => I | missense | 0.0002098 | 25 | 119162 | 0 | 0.13 | 0.016 | |
ssr5_human | 113 | 3.26x26 | TM3 | R => H | missense | 4.196e-05 | 5 | 119150 | 0 | 0.02 | 1.0 | |
ssr5_human | 114 | 3.27x27 | TM3 | L => M | missense | 8.393e-06 | 1 | 119152 | 0 | 0.05 | 0.964 | |
ssr5_human | 116 | 3.29x29 | TM3 | M => V | missense | 8.396e-06 | 1 | 119110 | 0 | 0.0 | 0.438 | |
ssr5_human | 117 | 3.30x30 | TM3 | T => M | missense | 0.00121 | 144 | 119020 | 0 | 0.0 | 0.984 | |
ssr5_human | 120 | 3.33x33 | TM3 | G => S | missense | 1.681e-05 | 2 | 118970 | 0 | 0.37 | 1.0 | |
ssr5_human | 121 | 3.34x34 | TM3 | V => I | missense | 4.204e-05 | 5 | 118946 | 0 | 1.0 | 0.015 | |
ssr5_human | 134 | 3.47x47 | TM3 | S => R | missense | 0.0001099 | 13 | 118340 | 0 | 0.0 | 1.0 | |
ssr5_human | 135 | 3.48x48 | TM3 | V => M | missense | 7.608e-05 | 9 | 118296 | 0 | 0.07 | 0.404 | |
ssr5_human | 137 | 3.50x50 | TM3 | R => C | missense | 4.235e-05 | 5 | 118056 | 0 | 0.01 | 1.0 | SodiumPocket MicroSwitch GP (contact) |
ssr5_human | 137 | 3.50x50 | TM3 | R => S | missense | 8.471e-06 | 1 | 118056 | 0 | 0.0 | 0.999 | SodiumPocket MicroSwitch GP (contact) |
ssr5_human | 137 | 3.50x50 | TM3 | R => H | missense | 4.236e-05 | 5 | 118026 | 0 | 0.0 | 1.0 | SodiumPocket MicroSwitch GP (contact) |
ssr5_human | 138 | 3.51x51 | TM3 | Y => H | missense | 1.696e-05 | 2 | 117958 | 0 | 0.0 | 0.999 | |
ssr5_human | 140 | 3.53x53 | TM3 | A => V | missense | 2.554e-05 | 3 | 117448 | 0 | 0.0 | 0.999 | GP (contact) |
ssr5_human | 141 | 3.54x54 | TM3 | V => A | missense | 0.0002473 | 29 | 117258 | 0 | 0.0 | 0.771 | GP (contact) |
ssr5_human | 142 | 3.55x55 | TM3 | V => M | missense | 8.542e-06 | 1 | 117068 | 0 | 0.0 | 1.0 | GP (contact) |
ssr5_human | 143 | 3.56x56 | TM3 | H => Q | missense | 8.602e-06 | 1 | 116252 | 0 | 0.0 | 0.762 | GP (contact) |
ssr5_human | 144 | 34.50x50 | ICL2 | P => L | missense | 2.603e-05 | 3 | 115270 | 0 | 0.01 | 1.0 | GP (contact) |
ssr5_human | 144 | 34.50x50 | ICL2 | P => Q | missense | 8.675e-06 | 1 | 115270 | 0 | 0.0 | 1.0 | GP (contact) |
ssr5_human | 146 | 34.52x52 | ICL2 | S => R | missense | 8.796e-06 | 1 | 113690 | 0 | 1.0 | 0.001 | PTM (Phosphorylation) GP (contact) |
ssr5_human | 149 | 34.55x55 | ICL2 | R => C | missense | 3.605e-05 | 4 | 110968 | 0 | 0.0 | 0.912 | GP (contact) |
ssr5_human | 149 | 34.55x55 | ICL2 | R => H | missense | 0.0001983 | 22 | 110928 | 0 | 0.01 | 0.04 | GP (contact) |
ssr5_human | 151 | 34.57x57 | ICL2 | R => C | missense | 9.234e-06 | 1 | 108298 | 0 | 0.0 | 1.0 | GP (contact) |
ssr5_human | 152 | 4.38x38 | TM4 | R => C | missense | 9.245e-06 | 1 | 108168 | 0 | 0.0 | 0.984 | |
ssr5_human | 152 | 4.38x38 | TM4 | R => H | missense | 3.72e-05 | 4 | 107528 | 0 | 0.06 | 0.967 | |
ssr5_human | 153 | 4.39x39 | TM4 | P => L | missense | 1.858e-05 | 2 | 107664 | 0 | 0.01 | 1.0 | |
ssr5_human | 154 | 4.40x40 | TM4 | R => C | missense | 9.299e-06 | 1 | 107542 | 0 | 0.0 | 0.941 | |
ssr5_human | 154 | 4.40x40 | TM4 | R => H | missense | 1.87e-05 | 2 | 106924 | 0 | 0.07 | 0.041 | |
ssr5_human | 159 | 4.45x45 | TM4 | A => V | missense | 1.024e-05 | 1 | 97638 | 0 | 1.0 | 0.463 | |
ssr5_human | 160 | 4.46x46 | TM4 | S => N | missense | 1.026e-05 | 1 | 97436 | 0 | 1.0 | 0.998 | |
ssr5_human | 161 | 4.47x47 | TM4 | A => S | missense | 2.086e-05 | 2 | 95868 | 0 | 0.21 | 0.999 | |
ssr5_human | 162 | 4.48x48 | TM4 | A => V | missense | 0.0001478 | 14 | 94694 | 1 | 0.04 | 0.69 | |
ssr5_human | 163 | 4.49x49 | TM4 | A => P | missense | 1.056e-05 | 1 | 94684 | 0 | 0.0 | 0.659 | |
ssr5_human | 163 | 4.49x49 | TM4 | A => S | missense | 1.056e-05 | 1 | 94684 | 0 | 0.0 | 0.307 | |
ssr5_human | 170 | 4.56x56 | TM4 | M => V | missense | 2.17e-05 | 2 | 92176 | 0 | 1.0 | 0.034 | |
ssr5_human | 178 | 4.64x65 | TM4 | A => T | missense | 1.111e-05 | 1 | 90030 | 0 | 0.02 | 0.699 | |
ssr5_human | 178 | 4.64x65 | TM4 | A => V | missense | 3.344e-05 | 3 | 89722 | 0 | 0.02 | 0.167 | |
ssr5_human | 180 | ECL2 | V => M | missense | 3.31e-05 | 3 | 90622 | 0 | 0.0 | 0.949 | ||
ssr5_human | 183 | ECL2 | G => D | missense | 1.085e-05 | 1 | 92138 | 0 | 0.26 | 0.988 | ||
ssr5_human | 184 | ECL2 | G => S | missense | 4.338e-05 | 4 | 92202 | 0 | 0.7 | 0.355 | ||
ssr5_human | 188 | 45.52x52 | ECL2 | A => T | missense | 2.121e-05 | 2 | 94282 | 0 | 0.0 | 0.004 | |
ssr5_human | 194 | 5.31x32 | TM5 | V => M | missense | 3.036e-05 | 3 | 98798 | 0 | 0.07 | 0.944 | |
ssr5_human | 196 | 5.33x34 | TM5 | L => P | missense | 2.978e-05 | 3 | 100722 | 0 | 0.05 | 0.968 | |
ssr5_human | 196 | 5.33x34 | TM5 | L => R | missense | 9.928e-06 | 1 | 100722 | 0 | 0.33 | 0.139 | |
ssr5_human | 198 | 5.35x36 | TM5 | G => R | missense | 9.838e-06 | 1 | 101650 | 0 | 0.49 | 0.055 | |
ssr5_human | 198 | 5.35x36 | TM5 | G => D | missense | 9.819e-06 | 1 | 101842 | 0 | 0.18 | 0.645 | |
ssr5_human | 199 | 5.36x37 | TM5 | A => T | missense | 4.892e-05 | 5 | 102198 | 0 | 0.67 | 0.999 | |
ssr5_human | 200 | 5.37x38 | TM5 | V => I | missense | 0.0002023 | 21 | 103814 | 0 | 0.06 | 0.024 | |
ssr5_human | 203 | 5.40x41 | TM5 | I => V | missense | 1.885e-05 | 2 | 106114 | 0 | 0.64 | 0.014 | |
ssr5_human | 207 | 5.44x45 | TM5 | V => M | missense | 1.833e-05 | 2 | 109134 | 0 | 0.08 | 0.99 | |
ssr5_human | 210 | 5.47x47 | TM5 | F => L | missense | 8.994e-06 | 1 | 111186 | 0 | 0.0 | 0.997 | SodiumPocket MicroSwitch |
ssr5_human | 212 | 5.49x49 | TM5 | A => T | missense | 3.558e-05 | 4 | 112410 | 0 | 0.29 | 0.386 | |
ssr5_human | 212 | 5.49x49 | TM5 | A => V | missense | 9.777e-05 | 11 | 112504 | 0 | 0.46 | 0.465 | |
ssr5_human | 213 | 5.50x50 | TM5 | P => L | missense | 2.654e-05 | 3 | 113030 | 0 | 0.0 | 1.0 | SodiumPocket MicroSwitch |
ssr5_human | 220 | 5.57x57 | TM5 | C => G | missense | 8.666e-06 | 1 | 115396 | 0 | 0.0 | 0.998 | |
ssr5_human | 223 | 5.60x60 | TM5 | L => F | missense | 8.639e-06 | 1 | 115754 | 0 | 0.08 | 1.0 | |
ssr5_human | 224 | 5.61x61 | TM5 | I => L | missense | 8.629e-06 | 1 | 115888 | 0 | 0.06 | 0.991 | GP (contact) |
ssr5_human | 224 | 5.61x61 | TM5 | I => M | missense | 8.632e-06 | 1 | 115852 | 0 | 0.02 | 0.999 | GP (contact) |
ssr5_human | 226 | 5.63x63 | TM5 | V => A | missense | 1.723e-05 | 2 | 116058 | 0 | 0.21 | 0.015 | |
ssr5_human | 229 | 5.66x66 | TM5 | R => W | missense | 8.628e-06 | 1 | 115902 | 0 | 0.02 | 0.955 | GP (contact) |
ssr5_human | 230 | 5.67x67 | TM5 | A => V | missense | 6.921e-05 | 8 | 115592 | 0 | 0.08 | 0.066 | GP (contact) |
ssr5_human | 230 | 5.67x67 | TM5 | A => E | missense | 8.651e-06 | 1 | 115592 | 0 | 0.0 | 0.891 | GP (contact) |
ssr5_human | 231 | 5.68x68 | TM5 | A => V | missense | 2.602e-05 | 3 | 115298 | 0 | 0.38 | 0.016 | GP (contact) |
ssr5_human | 231 | 5.68x68 | TM5 | A => G | missense | 1.735e-05 | 2 | 115298 | 0 | 0.43 | 0.388 | GP (contact) |
ssr5_human | 233 | ICL3 | V => M | missense | 8.647e-06 | 1 | 115650 | 0 | 0.2 | 0.079 | ||
ssr5_human | 234 | ICL3 | R => C | missense | 2.592e-05 | 3 | 115736 | 0 | 0.0 | 0.999 | ||
ssr5_human | 234 | ICL3 | R => H | missense | 8.64e-06 | 1 | 115736 | 0 | 0.0 | 0.999 | ||
ssr5_human | 235 | ICL3 | V => M | missense | 8.622e-05 | 10 | 115986 | 0 | 0.01 | 0.833 | ||
ssr5_human | 238 | 6.25x25 | TM6 | V => M | missense | 0.0001374 | 16 | 116408 | 0 | 0.08 | 0.015 | GP (contact) |
ssr5_human | 239 | 6.26x26 | TM6 | R => G | missense | 3.438e-05 | 4 | 116342 | 0 | 0.0 | 0.055 | GP (contact) |
ssr5_human | 239 | 6.26x26 | TM6 | R => W | missense | 1.719e-05 | 2 | 116342 | 0 | 0.0 | 0.979 | GP (contact) |
ssr5_human | 239 | 6.26x26 | TM6 | R => Q | missense | 4.29e-05 | 5 | 116554 | 0 | 0.06 | 0.874 | GP (contact) |
ssr5_human | 240 | 6.27x27 | TM6 | R => W | missense | 0.001664 | 194 | 116554 | 0 | 0.0 | 1.0 | |
ssr5_human | 240 | 6.27x27 | TM6 | R => Q | missense | 8.565e-06 | 1 | 116748 | 0 | 0.0 | 0.998 | |
ssr5_human | 241 | 6.28x28 | TM6 | R => C | missense | 1.712e-05 | 2 | 116814 | 0 | 0.0 | 0.999 | GP (contact) |
ssr5_human | 241 | 6.28x28 | TM6 | R => L | missense | 1.711e-05 | 2 | 116918 | 0 | 0.02 | 0.999 | GP (contact) |
ssr5_human | 241 | 6.28x28 | TM6 | R => H | missense | 8.553e-06 | 1 | 116918 | 0 | 0.03 | 0.999 | GP (contact) |
ssr5_human | 242 | 6.29x29 | TM6 | S => L | missense | 1.708e-05 | 2 | 117122 | 0 | 0.0 | 0.667 | PTM (Phosphorylation) GP (contact) |
ssr5_human | 242 | 6.29x29 | TM6 | S => W | missense | 8.538e-06 | 1 | 117122 | 0 | 0.01 | 0.99 | PTM (Phosphorylation) GP (contact) |
ssr5_human | 244 | 6.31x31 | TM6 | R => G | missense | 8.514e-06 | 1 | 117456 | 0 | 0.07 | 0.871 | |
ssr5_human | 244 | 6.31x31 | TM6 | R => W | missense | 8.514e-06 | 1 | 117456 | 0 | 0.0 | 0.983 | |
ssr5_human | 244 | 6.31x31 | TM6 | R => Q | missense | 2.552e-05 | 3 | 117564 | 0 | 0.02 | 0.898 | |
ssr5_human | 244 | 6.31x31 | TM6 | R => L | missense | 8.506e-06 | 1 | 117564 | 0 | 0.0 | 0.871 | |
ssr5_human | 247 | 6.34x34 | TM6 | T => A | missense | 8.472e-06 | 1 | 118036 | 0 | 0.0 | 0.997 | SodiumPocket MicroSwitch PTM (Phosphorylation) |
ssr5_human | 247 | 6.34x34 | TM6 | T => M | missense | 2.542e-05 | 3 | 118024 | 0 | 0.0 | 0.999 | SodiumPocket MicroSwitch PTM (Phosphorylation) |
ssr5_human | 248 | 6.35x35 | TM6 | R => C | missense | 0.001532 | 181 | 118148 | 1 | 0.01 | 0.999 | |
ssr5_human | 248 | 6.35x35 | TM6 | R => H | missense | 2.538e-05 | 3 | 118208 | 0 | 0.03 | 0.999 | |
ssr5_human | 250 | 6.37x37 | TM6 | V => M | missense | 3.376e-05 | 4 | 118498 | 0 | 0.0 | 0.999 | GP (contact) |
ssr5_human | 251 | 6.38x38 | TM6 | L => S | missense | 0.002782 | 330 | 118638 | 6 | 0.27 | 0.397 | |
ssr5_human | 258 | 6.45x45 | TM6 | A => V | missense | 8.402e-06 | 1 | 119024 | 0 | 1.0 | 0.007 | |
ssr5_human | 260 | 6.47x47 | TM6 | C => Y | missense | 8.385e-06 | 1 | 119266 | 0 | 0.0 | 0.999 | |
ssr5_human | 263 | 6.50x50 | TM6 | P => L | missense | 5.025e-05 | 6 | 119412 | 0 | 0.0 | 1.0 | SodiumPocket MicroSwitch |
ssr5_human | 267 | 6.54x54 | TM6 | V => I | missense | 8.369e-06 | 1 | 119488 | 0 | 0.24 | 0.011 | |
ssr5_human | 270 | 6.57x57 | TM6 | V => I | missense | 8.364e-05 | 10 | 119558 | 0 | 0.2 | 0.095 | |
ssr5_human | 273 | 6.60x60 | TM6 | A => S | missense | 1.672e-05 | 2 | 119594 | 0 | 0.24 | 0.938 | |
ssr5_human | 274 | 6.61x61 | TM6 | V => M | missense | 0.0001254 | 15 | 119606 | 0 | 0.16 | 0.709 | |
ssr5_human | 278 | ECL3 | Q => K | missense | 8.361e-06 | 1 | 119602 | 0 | 0.19 | 0.036 | ||
ssr5_human | 279 | 7.28x27 | TM7 | E => K | missense | 0.0004849 | 58 | 119618 | 1 | 0.18 | 0.997 | |
ssr5_human | 281 | 7.30x29 | TM7 | A => T | missense | 3.348e-05 | 4 | 119490 | 0 | 0.49 | 0.028 | |
ssr5_human | 283 | 7.32x31 | TM7 | A => T | missense | 2.513e-05 | 3 | 119380 | 0 | 0.5 | 0.022 | |
ssr5_human | 286 | 7.35x34 | TM7 | Y => C | missense | 8.35e-05 | 10 | 119758 | 0 | 0.01 | 0.999 | |
ssr5_human | 287 | 7.36x35 | TM7 | F => V | missense | 8.349e-06 | 1 | 119768 | 0 | 0.34 | 0.09 | |
ssr5_human | 288 | 7.37x36 | TM7 | F => L | missense | 8.349e-06 | 1 | 119778 | 0 | 0.49 | 0.41 | |
ssr5_human | 295 | 7.44x43 | TM7 | A => T | missense | 8.349e-06 | 1 | 119768 | 0 | 0.02 | 0.999 | SodiumPocket MicroSwitch |
ssr5_human | 296 | 7.45x45 | TM7 | N => T | missense | 2.505e-05 | 3 | 119770 | 0 | 0.0 | 0.998 | |
ssr5_human | 297 | 7.46x46 | TM7 | S => G | missense | 8.35e-06 | 1 | 119766 | 0 | 0.0 | 0.994 | |
ssr5_human | 298 | 7.47x47 | TM7 | C => Y | missense | 8.352e-06 | 1 | 119736 | 0 | 0.0 | 0.999 | |
ssr5_human | 298 | 7.47x47 | TM7 | C => F | missense | 8.352e-06 | 1 | 119736 | 0 | 0.0 | 0.999 | |
ssr5_human | 301 | 7.50x50 | TM7 | P => T | missense | 8.354e-06 | 1 | 119704 | 0 | 0.0 | 1.0 | SodiumPocket MicroSwitch |
ssr5_human | 302 | 7.51x51 | TM7 | V => I | missense | 0.0001755 | 21 | 119654 | 0 | 1.0 | 0.016 | |
ssr5_human | 305 | 7.54x54 | TM7 | G => S | missense | 4.183e-05 | 5 | 119534 | 0 | 0.05 | 0.999 | |
ssr5_human | 306 | 7.55x55 | TM7 | F => L | missense | 1.673e-05 | 2 | 119512 | 0 | 0.06 | 0.978 | GP (contact) |
ssr5_human | 312 | 8.51x51 | H8 | R => C | missense | 5.874e-05 | 7 | 119168 | 0 | 0.0 | 0.997 | GP (contact) |
ssr5_human | 312 | 8.51x51 | H8 | R => H | missense | 1.679e-05 | 2 | 119124 | 0 | 0.02 | 0.997 | GP (contact) |
ssr5_human | 312 | 8.51x51 | H8 | R => L | missense | 8.395e-06 | 1 | 119124 | 0 | 0.0 | 0.997 | GP (contact) |
ssr5_human | 318 | 8.57x57 | H8 | V => F | missense | 3.369e-05 | 4 | 118730 | 0 | 0.0 | 0.527 | |
ssr5_human | 322 | C-term | R => C | missense | 8.449e-06 | 1 | 118358 | 0 | 0.04 | 0.014 | ||
ssr5_human | 322 | C-term | R => L | missense | 1.69e-05 | 2 | 118312 | 0 | 0.04 | 0.252 | ||
ssr5_human | 322 | C-term | R => H | missense | 1.69e-05 | 2 | 118312 | 0 | 0.16 | 0.014 | ||
ssr5_human | 324 | C-term | G => D | missense | 8.462e-06 | 1 | 118172 | 0 | 0.62 | 0.558 | ||
ssr5_human | 327 | C-term | A => V | missense | 0.0001527 | 18 | 117888 | 0 | 1.0 | 0.002 | ||
ssr5_human | 330 | C-term | A => T | missense | 5.107e-05 | 6 | 117484 | 0 | 0.26 | 0.336 | ||
ssr5_human | 331 | C-term | D => Y | missense | 8.524e-06 | 1 | 117322 | 0 | 0.0 | 0.808 | ||
ssr5_human | 331 | C-term | D => E | missense | 8.54e-06 | 1 | 117096 | 0 | 0.86 | 0.021 | ||
ssr5_human | 332 | C-term | A => T | missense | 8.551e-06 | 1 | 116942 | 0 | 0.56 | 0.003 | ||
ssr5_human | 333 | C-term | T => M | missense | 0.007813 | 911 | 116602 | 24 | 0.12 | 0.014 | PTM (Phosphorylation) | |
ssr5_human | 335 | C-term | P => L | missense | 0.5386 | 62255 | 115580 | 17132 | 0.12 | 0.041 | ||
ssr5_human | 336 | C-term | R => C | missense | 8.807e-06 | 1 | 113540 | 0 | 0.02 | 0.781 | ||
ssr5_human | 336 | C-term | R => H | missense | 8.817e-05 | 10 | 113416 | 0 | 0.03 | 0.636 | ||
ssr5_human | 341 | C-term | R => W | missense | 0.0001338 | 15 | 112124 | 0 | 0.01 | 0.409 | ||
ssr5_human | 341 | C-term | R => Q | missense | 2.683e-05 | 3 | 111812 | 0 | 0.46 | 0.045 | ||
ssr5_human | 342 | C-term | Q => K | missense | 8.936e-06 | 1 | 111908 | 0 | 0.82 | 0.013 | ||
ssr5_human | 345 | C-term | E => Q | missense | 9.041e-06 | 1 | 110606 | 0 | 0.22 | 0.008 | ||
ssr5_human | 345 | C-term | E => D | missense | 9.118e-06 | 1 | 109670 | 0 | 0.45 | 0.058 | ||
ssr5_human | 346 | C-term | A => V | missense | 2.761e-05 | 3 | 108670 | 0 | 0.23 | 0.003 | ||
ssr5_human | 347 | C-term | T => R | missense | 9.2e-06 | 1 | 108694 | 0 | 0.44 | 0.343 | PTM (Phosphorylation) | |
ssr5_human | 348 | C-term | P => L | missense | 3.688e-05 | 4 | 108468 | 0 | 0.5 | 0.0 | ||
ssr5_human | 349 | C-term | P => R | missense | 1.119e-05 | 1 | 89364 | 0 | 0.14 | 0.549 | ||
ssr5_human | 350 | C-term | A => T | missense | 0.000101 | 9 | 89100 | 0 | 1.0 | 0.002 | ||
ssr5_human | 352 | C-term | R => C | missense | 3.493e-05 | 3 | 85890 | 0 | 0.07 | 0.015 | ||
ssr5_human | 352 | C-term | R => H | missense | 2.329e-05 | 2 | 85884 | 0 | 0.13 | 0.003 | ||
ssr5_human | 353 | C-term | A => T | missense | 0.0001534 | 13 | 84734 | 0 | 0.89 | 0.038 | ||
ssr5_human | 354 | C-term | A => T | missense | 7.267e-05 | 6 | 82570 | 0 | 0.57 | 0.001 | ||
ssr5_human | 356 | C-term | N => H | missense | 9.836e-05 | 8 | 81338 | 0 | 0.0 | 0.694 | ||
ssr5_human | 357 | C-term | G => R | missense | 0.00195 | 156 | 79982 | 0 | 0.03 | 0.066 | ||
ssr5_human | 357 | C-term | G => A | missense | 1.258e-05 | 1 | 79516 | 0 | 0.0 | 0.354 | ||
ssr5_human | 358 | C-term | L => P | missense | 1.27e-05 | 1 | 78734 | 0 | 0.26 | 0.003 | ||
ssr5_human | 360 | C-term | Q => R | missense | 0.0002756 | 21 | 76206 | 0 | 0.0 | 0.5 | ||
ssr5_human | 364 | C-term | L => P | missense | 5.579e-05 | 4 | 71698 | 0 | nan | 0.863 |
Residue
- deleterious missense variants are shown in red
- tolerated missense variants are shown in green
- loss of function mutations ('stop gained' or 'frameshift' in the coding region) are shown in blue